Gramicidin S TFA salt

CAS: 113-73-5

Ref. 3D-FG166334

Product Information

• Name: Gramicidin S TFA salt
• Brand: Biosynth
• Description: Gramicidin S TFA salt is a cyclic peptide antibiotic, which is originally derived from the soil bacterium Bacillus brevis. Its mode of action involves disrupting bacterial cell membranes by integrating into the lipid bilayer, which affects membrane integrity and leads to cell lysis. The unique cyclic dodecapeptide structure allows Gramicidin S to interact specifically with membrane lipids, forming pores that increase permeability and ion flux.In terms of applications, Gramicidin S is primarily used in research settings for studying membrane dynamics and permeability. Its potent antibiotic activity makes it a valuable compound in bacteriological studies, particularly for investigating multi-drug resistance mechanisms and testing novel antimicrobial strategies. Additionally, due to its peptide nature, it serves as a model compound for the design of synthetic analogs aimed at overcoming bacterial resistance.

Chemical properties

• Molecular weight: 1,141.45 g/mol
• Formula: C₆₀H₉₂N₁₂O₁₀(freebase)
• Purity: Min. 95 Area-%
• Color/Form: White Off-White Powder