Griselimycin

CAS: 26034-16-2

Ref. 3D-FG178240

Product Information

• Name: Griselimycin
• Brand: Biosynth
• Description: Griselimycin is an antibiotic, which is derived from the bacterial genus *Streptomyces*. This compound exhibits its mode of action by targeting bacterial protein synthesis, specifically binding to the DNA polymerase sliding clamp, thereby inhibiting replication and cell division in a range of bacterial pathogens. Griselimycin has been the focus of renewed scientific interest due to its potent activity against Mycobacterium tuberculosis, including multi-drug-resistant strains. The compound’s unique mode of action makes it a promising candidate for further development in the treatment of tuberculosis and potentially other bacterial infections that have developed resistance to more commonly used antibiotics. Advances in understanding its biosynthesis have facilitated semi-synthetic modifications, potentially enhancing its pharmacokinetic properties and antimicrobial spectrum. The applications of Griselimycin extend to research contexts where understanding resistance mechanisms and novel antibiotic development are critical. Continued exploration of this compound may contribute significantly to addressing the global challenge of antibiotic resistance.

Chemical properties

• Molecular weight: 1112.72092
• Formula: C₅₇H₉₆N₁₀O₁₂
• Purity: Min. 95%