N-Glycidyl phthalimide

CAS: 5455-98-1

Ref. 3D-FG23687

Product Information

• Name: N-Glycidyl phthalimide
• Synonyms: 2-(2-Oxiranylmethyl)-1H-isoindole-1,3(2H)-dioneN-(2,3-Epoxypropyl)phthalimide2,3-Epoxypropylphthalimide, (Phthalimidomethyl)Oxirane, 1H-Isoindole-1,3(2H)-dione, 2-(2-oxiranylmethyl)-, 1H-Isoindole-1,3(2H)-dione, 2-(oxiranylmethyl)-, 2,3-Epoxypropylphthalimide, 2-(2-Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione, 2-(Oxiran-2-Ylmethyl)-1H-Isoindole-1,3(2H)-Dione, 2-(Oxiran-2-Ylmethyl)Isoindoline-1,3-Dione, 2-(Oxiran-2-ylmethyl)-2,3-dihydro-1H-isoindole-1,3-dione, 2-(Oxiran-2-ylmethyl)isoindole-1,3-dione, 2-(Oxiranylmethyl)-1H-Isoindole-1,3(2H)-Dione, 2-(Oxiranylmethyl)-1H-Isoindole-3(2H)-Dione, 2-(Phthalimidomethyl)oxirane, 2-[(Oxiranyl)methyl]isoindole-1,3-dione, Denacol EX 731, Denacolex731, N-(2,3-Epoxypropan-1-yl)phthalimide, N-(2,3-Epoxypropyl) Phthalmide, N-(2,3-Epoxypropyl)-2-Phthalimide, N-(2,3-Epoxypropyl)-O-Phthalimide, N-(2,3-Epoxypropyl)-Phthalamide, N-(2,3-Epoxypropyl)-Phthalimid, N-Glycidylphthalimide, N-Glycidyphthalimide, N-Oxiranylmethylphthalimide, NSC 7244, Phthalimide, N-(2,3-epoxypropyl)-

Description

N-Glycidyl phthalimide is a dithiocarbamic compound that has been shown to inhibit blood coagulation. It is synthesized by the reaction of chloroacetic acid with phthalic anhydride and glycine, which leads to the formation of a homochiral product. N-Glycidyl phthalimide has been shown to be effective in vivo in animal models and has biological relevance, as it can be enzymatically hydrolyzed to form 5-hydroxytetrahydrofolate, which is necessary for DNA synthesis. The rate enhancement of this process may be due to the carbonyl group on the molecule, which interacts with enzymes such as carboxypeptidase A and cathepsin C.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.19 g/mol
• Formula: C₁₁H₉NO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2
• InChI key: InChIKey=DUILGEYLVHGSEE-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2C(=O)N1CC1CO1