(R)-(-)-Glycidyl benzyl ether

CAS: 14618-80-5

Ref. 3D-FG30975

Product Information

• Name: (R)-(-)-Glycidyl benzyl ether
• Synonyms: (R)-(-)-2-(Benzyloxymethyl)oxirane, (+)-(Benzyloxymethyl)oxirane, (+)-Benzyl glycidyl ether, (-)-(R)-1,2-Epoxy-3-(benzyloxy)propane, (-)-2-(Benzyloxymethyl)oxirane, (-)-Benzyl-(R)-Glycidylether, (-)-Benzyl-(R)-glycidyl ether, (-)-Glycidyl benzyl ether, (2R)-2-(Phenylmethoxymethyl)oxirane, (2R)-2-[(Phenylmethoxy)methyl]oxirane, (2R)-2-[(benzyloxy)methyl]oxirane, (2S)-2-[(benzyloxy)methyl]oxirane, (R)-(-)-Benzylglycidol, (R)-1-Benzyloxy-2,3-epoxypropane, (R)-2-(Benzyloxymethyl)oxirane, (R)-Benzyloxymethyl-Oxirane, (R)-Benzyloxymethyloxirane, (R)-Glycidol benzyl ether, (R)-O-Benzylglycidol, (S)-Benzyl glycidyl ether, 2-[(Benzyloxy)methyl]oxirane, Benzyl (R)-2-epoxypropyl ether, Oxirane, 2-[(phenylmethoxy)methyl]-, Oxirane, 2-[(phenylmethoxy)methyl]-, (2R)-, Oxirane, [(phenylmethoxy)methyl]-, Oxirane, [(phenylmethoxy)methyl]-, (2R)-, Oxirane, [(phenylmethoxy)methyl]-, (R)-, Propane, 1-(benzyloxy)-2,3-epoxy-, (R)-

Description

(R)-(-)-Glycidyl benzyl ether is an epoxide that can be synthesized by the reaction of glycidol and benzyl chloride with a chiral catalyst. This compound has been shown to have good oral bioavailability in vivo, and it is also stereoselective. The synthesis of (R)-(-)-Glycidyl benzyl ether involves a four-step process with a yield of around 60%. The first step involves the synthesis of glycidol, which can be accomplished with the help of an organometallic reagent such as n-butyllithium. The second step involves the addition of benzyl chloride to glycidol to produce 1,2-epoxycyclohexane. The third step entails hydrogenation of 1,2-epoxycyclohexane to form (R)-(-)-Glycidyl benzyl ether in high yield. Finally, the fourth step is the removal of hydrogen chloride

• Brand: Biosynth

Chemical properties

• Molecular weight: 164.2 g/mol
• Formula: C₁₀H₁₂O₂
• Purity: Min. 95%