(R)-(-)-Glycidyl benzyl ether

Ref. 3D-FG30975

Product Information

• Name: (R)-(-)-Glycidyl benzyl ether
• Synonyms: (R)-(-)-2-(Benzyloxymethyl)oxirane
• Brand: Biosynth
• Description: (R)-(-)-Glycidyl benzyl ether is an epoxide that can be synthesized by the reaction of glycidol and benzyl chloride with a chiral catalyst. This compound has been shown to have good oral bioavailability in vivo, and it is also stereoselective. The synthesis of (R)-(-)-Glycidyl benzyl ether involves a four-step process with a yield of around 60%. The first step involves the synthesis of glycidol, which can be accomplished with the help of an organometallic reagent such as n-butyllithium. The second step involves the addition of benzyl chloride to glycidol to produce 1,2-epoxycyclohexane. The third step entails hydrogenation of 1,2-epoxycyclohexane to form (R)-(-)-Glycidyl benzyl ether in high yield. Finally, the fourth step is the removal of hydrogen chloride

Chemical properties

• Molecular weight: 164.2 g/mol
• Formula: C₁₀H₁₂O₂
• Purity: Min. 95%