(Z&E)-Guggulsterone

CAS: 95975-55-6

Ref. 3D-FG41868

Product Information

• Name: (Z&E)-Guggulsterone
• Synonyms: Pregna-4,17(20)-diene-3,16-dione
• Brand: Biosynth
• Description: (Z&E)-Guggulsterone is a steroidal compound, derived from the resin of the Commiphora mukul plant, commonly known as Guggul. This plant source has been traditionally utilized in Ayurvedic medicine, and modern extraction techniques allow for the isolation of guggulsterones, including the (Z&E) isomers, which are recognized for their bioactive properties. The mode of action for (Z&E)-Guggulsterone involves the modulation of nuclear receptors, specifically the farnesoid X receptor (FXR) and the estrogen receptor, which play crucial roles in lipid metabolism and inflammatory pathways. This modulation can lead to lowered cholesterol levels and an anti-inflammatory effect.

Chemical properties

• Molecular weight: 312.45 g/mol
• Formula: C₂₁H₂₈O₂
• Purity: Min. 95%
• Color/Form: Off-White Yellow Powder
• InChI: InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
• InChI key: InChIKey=WDXRGPWQVHZTQJ-OSJVMJFVSA-N
• SMILES: C/C=C1\C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C