18-α-Glycyrrhetinic acid

CAS: 1449-05-4

Ref. 3D-FG67268

Product Information

• Name: 18-α-Glycyrrhetinic acid
• Synonyms: 3beta-Hydroxy-11-oxo-18alpha,20beta-olean-12-en-29-oic acid 18 beta-Glycyrrhetintic acid 18A-Glycyrrhetinic acid, (3Beta)-3-Hydroxy-11-Oxoolean-12-En-30-Oate, (3Beta)-3-Hydroxy-11-Oxoolean-12-En-30-Oic Acid, (3Beta,18Alpha)-3-Hydroxy-11-Oxoolean-12-En-30-Oic Acid, (3beta,18alpha,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic acid, (3β,18α,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid, 18-Isoglycyrrhetinic acid, 18-alpha-Olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-, 18-β Glycyrrhetinic Acid, 18α-Glycyrrhetic acid, 18α-Glycyrrhetinic acid, 18α-Olean-12-en-30-oic acid, 3β-hydroxy-11-oxo-, 3-Hydroxy-11-Oxoolean-12-En-29-Oic Acid, 3-beta-Hydroxy-11-oxo-18-alpha-olean-12-en-30-oic acid, Brn 2956366, Ccris 3963, Nsc 35350, Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,18α,20β)-, Stx 353, beta-Glycyrrhetinic acid, β-Glycyrrhetinic acid

Description

18-alpha-Glycyrrhetinic acid is a natural compound that has been shown to have anti-inflammatory properties. 18-alpha-Glycyrrhetinic acid inhibits the release of inflammatory cytokines, such as tumor necrosis factor alpha (TNFα) and interleukin 1β (IL1β), from 3T3-L1 preadipocytes. It also acts as an inhibitor of toll-like receptor 4 (TLR4) signaling in mouse models of colitis. Glycyrrhetinic acid was also found to inhibit the polymerase chain reaction in human cells, and it has been shown to inhibit the growth of murine hepatoma cells in vivo. This compound also has inhibitory effects on squamous cell carcinomas and neuronal death in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 470.68 g/mol
• Formula: C₃₀H₄₆O₄
• Purity: Min. 95 Area-%
• Color/Form: Powder