8-Geranyloxypsoralen

CAS: 7437-55-0

Ref. 3D-FG67820

Product Information

• Name: 8-Geranyloxypsoralen
• Synonyms: 5-Benzofuranacrylic acid, 7-(geranyloxy)-6-hydroxy-, δ-lactone, 5-Benzofuranacrylicacid, 7-(geranyloxy)-6-hydroxy-, d-lactone, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-, 7H-Furo[3,2-g][1]benzopyran-7-one,9-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)-, 9-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-

Description

8-Geranyloxypsoralen is a natural compound found in grapefruit and bergamot. It is used for the treatment of psoriasis, which is a chronic inflammatory skin disease that causes red, scaly patches to appear on the skin. 8-Geranyloxypsoralen inhibits the rate of DNA synthesis in cells by binding to p-glycoprotein (Pgp), affecting drug transport from inside the cell to outside. This leads to an accumulation of drugs within the cell that are normally eliminated by Pgp. 8-Geranyloxypsoralen also has inhibitory properties against cancer cells and can be used as a chemotherapeutic agent. It may be able to reduce tumour size or stop its growth.8-Geranyloxypsoralen has been shown to have inhibitory effects on mouse monoclonal antibodies when it binds with dna in 3t3-l1 preadipocytes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 338.4 g/mol
• Formula: C₂₁H₂₂O₄
• Purity: Min. 95 Area-%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-19-17(10-12-23-19)13-16-7-8-18(22)25-20(16)21/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
• InChI key: InChIKey=SOVNCTNQAWWYAQ-OQLLNIDSSA-N
• SMILES: CC(C)=CCC/C(C)=C/COc1c2occc2cc2ccc(=O)oc12