Product Information
- (7β,20E)-7-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-dien-26-oic acid
- Ganoderenic acid d
- Ganoderenicacid d
- Lanosta-8,20(22)-dien-26-oic acid, 7-hydroxy-3,11,15,23-tetraoxo-, (7β,20E)-
Ganoderic acid D is a triterpenoid that exhibits cytotoxic properties against human cervical cancer cells. Ganoderic acid D has been shown to induce autophagy, a process in which the cell breaks down and recycles its own organelles for energy. This compound also induces apoptosis by inhibiting the synthesis of proteins. Ganoderic acid D has been shown to have significant cytotoxicity against human liver cancer cells, and it inhibits cholesterol synthesis by blocking the activity of key enzymes such as 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) and squalene synthase. Ganoderic acid D also blocks the production of prostaglandin E2 (PGE2) by inhibiting cyclooxygenase-2 (COX-2). Other studies have also demonstrated that this compound has anti-inflammatory effects when combined with adjuvant therapies.
Chemical properties
Technical inquiry about: 3D-FG74209 Ganoderenic acid D
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