5-Hydroxynicotinic acid

CAS: 27828-71-3

Ref. 3D-FH00338

Product Information

• Name: 5-Hydroxynicotinic acid
• Synonyms: 3-Hydroxypyridin-5-ylcarboxylic acid, 3-Pyridinecarboxylic Acid, 5-Hydroxy-, 5-Hydroxy-3-Pyridinecarboxylic Acid, 5-Hydroxy-Nicotinicaci, 5-Hydroxypyridine-3-Carboxylate, 5-Hydroxypyridine-3-Carboxylic Acid, NSC 606891, Nicotinic acid, 5-hydroxy-

Description

5-Hydroxynicotinic acid is a supramolecular compound that has been shown to bind to magnesium oxide and water molecules. The redox potential of 5-hydroxynicotinic acid is higher than the one of flavin. It is also a substrate for many enzymes, such as malonic acid decarboxylase and succinic semialdehyde dehydrogenase, which catalyze the reaction between 5-hydroxynicotinic acid and its tautomer, 2-hydroxyquinoline-3-carboxylic acid. The crystal structure of 5-hydroxynicotinic acid has been determined using X-ray crystallography. This compound has also been shown to have pharmacological activities in vitro on ventricular myocardium cells, including inhibition of enzyme activity and reduction in intracellular Ca2+ concentration.

• Brand: Biosynth

Chemical properties

• Molecular weight: 139.11 g/mol
• Formula: C₆H₅NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10)
• InChI key: InChIKey=ATTDCVLRGFEHEO-UHFFFAOYSA-N
• SMILES: O=C(O)c1cncc(O)c1