7-Hydroxycoumarin

CAS: 93-35-6

Ref. 3D-FH02253

Product Information

• Name: 7-Hydroxycoumarin
• Synonyms: 7-Hydroxy-2H-1-benzopyran-2-one7-Hydroxy-2H-chromen-2-oneUmbelliferone, 2H-1-Benzopyran-2-one, 7-hydroxy-, 7-Hidroxicumarina, 7-Hydroxy Coumarin, 7-Hydroxy-2-chromenone, 7-Hydroxy-2H-1-Benzopyran-2-One, 7-Hydroxycoumarine, 7-Hydroxycumarin, 7-Hydroxylcoumarin, 7-Oxycoumarin, 7-hydroxy-2H-chromen-2-one, Coumarin, 7-Hydroxy-, Hydrangin, Hydrangine, Nsc 19790, Skimmetin, Skimmetine, Umbelliferon, Umbelliferone

Description

7-Hydroxycoumarin is a coumarin derivative that is used as an analytical reagent. It has been shown to inhibit the growth of HL-60 cells, which are derived from human promyelocytic leukemia cells. 7-Hydroxycoumarin has also been shown to have anticarcinogenic properties and may be useful in the treatment of bowel diseases. This compound binds to a number of proteins and inhibits their activity, including recombinant cytochrome P450 enzymes (CYP1A2, CYP2D6, CYP3A4) and model systems such as rat liver microsomes and human liver microsomes. 7-Hydroxycoumarin also binds to chlorogenic acids found in natural compounds like coffee beans, apples, blueberries, green tea leaves and grapes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 162.14 g/mol
• Formula: C₉H₆O₃
• Purity: 90%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C9H6O3/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5,10H
• InChI key: InChIKey=ORHBXUUXSCNDEV-UHFFFAOYSA-N
• SMILES: O=c1ccc2ccc(O)cc2o1