Descarboxy 1-hydroxy ketorolac

CAS: 154476-25-2

Ref. 3D-FH09860

Product Information

• Name: Descarboxy 1-hydroxy ketorolac
• Synonyms: (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone
• Brand: Biosynth
• Description: Descarboxy 1-hydroxy ketorolac is a drug that is used to relieve moderate to severe pain. It consists of tromethamine and 1-hydroxy ketorolac, a non-steroidal anti-inflammatory agent. The mechanism of action is due to the conversion of 1-hydroxy ketorolac into ketorolac trometamol, which inhibits prostaglandin synthesis by blocking cyclooxygenase. This drug has been shown to have a long term effect in doses ranging from 12.5 mg twice daily for two weeks to 100 mg twice daily for six months. Descarboxy 1-hydroxy ketorolac is soluble in water and can be administered by intramuscular injection or intravenously as an infusion over 15 minutes.

Chemical properties

• Molecular weight: 227.26 g/mol
• Formula: C₁₄H₁₃NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C14H13NO2/c16-13-8-9-15-11(13)6-7-12(15)14(17)10-4-2-1-3-5-10/h1-7,13,16H,8-9H2
• InChI key: InChIKey=PPQHNULBCSHICE-UHFFFAOYSA-N
• SMILES: O=C(c1ccccc1)c1ccc2n1CCC2O