6-Hydroxy-2H-benzofuran-3-one

CAS: 6272-26-0

Ref. 3D-FH139688

Product Information

• Name: 6-Hydroxy-2H-benzofuran-3-one
• Synonyms: 3(2H)-Benzofuranone, 6-hydroxy-, 6-Hydroxy-2,3-dihydro-1-benzofuran-3-one, 6-Hydroxy-2,3-dihydrobenzo[b]furan-3-one, 6-Hydroxy-2,3-dihydrobenzofuran-3-one, 6-Hydroxy-3(2H)-benzofuranone, 6-Hydroxy-3-coumaranone, 6-Hydroxy-3-coumaranone~6-Hydroxy-2,3-dihydro-1-benzofuran-3-one, 6-Hydroxybenzofuran-3(2H)-one, 6-Hydroxybenzofuran-3-one, 6-hydroxy-1-benzofuran-3(2H)-one, NSC 37407

Description

6-Hydroxy-2H-benzofuran-3-one is a potent inhibitor that blocks the formation of aurones and aldehydes, which are markers for insulin sensitivity. This compound has also been shown to inhibit dna replication in vitro by binding to the enzyme beta-diketone reductase (BDKR) and inhibiting its activity. 6-Hydroxy-2H-benzofuran-3-one is a fluorinated benzofuran derivative with an erythrocentaurin core structure. It has been shown to be effective against Gram positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). 6HBF3 also inhibits the growth of Gram negative bacteria, including Mycobacterium tuberculosis and Mycobacterium avium complex. The mechanism of action is not fully understood but may involve blocking lipid synthesis or preventing the synthesis of precursors for bacterial cell wall biosynthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 150.13 g/mol
• Formula: C₈H₆O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H6O3/c9-5-1-2-6-7(10)4-11-8(6)3-5/h1-3,9H,4H2
• InChI key: InChIKey=GBDMODVZBPFQKI-UHFFFAOYSA-N
• SMILES: O=C1COc2cc(O)ccc21