3-Hydroxy-4-methylbenzoic acid

CAS: 586-30-1

Ref. 3D-FH14549

Product Information

• Name: 3-Hydroxy-4-methylbenzoic acid
• Synonyms: 3,4-Cresotic acid, 3-Hydroxy-p-toluic acid, 4-Methyl-3-hydroxybenzoic acid, Benzoic acid, 3-hydroxy-4-methyl-, NSC 67717, NSC 75850

Description

3-Hydroxy-4-methylbenzoic acid is a cardiotonic glycoside that has been used in the treatment of cardiac arrhythmia. It has been shown to inhibit the enzyme persulfate, which is involved in the activation of hydrogen peroxide and may be responsible for the therapeutic effect of 3-hydroxy-4-methylbenzoic acid. The inhibition of persulfate by 3-hydroxy-4-methylbenzoic acid may be due to an intramolecular hydrogen bond that is formed between the sulfonate group on 3-hydroxy-4 methyl benzoic acid and the hydroxyl group on 4-tert butylbenzoic acid. Animal studies have shown that this drug inhibits sodium urate crystal formation and excretion in urine samples. This drug also inhibits renal ammoniagenesis, which is a metabolic pathway where ammonia is converted to urea, thereby lowering blood levels of ammonia. The metabolism of

• Brand: Biosynth

Chemical properties

• Molecular weight: 152.15 g/mol
• Formula: C₈H₈O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H8O3/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,9H,1H3,(H,10,11)
• InChI key: InChIKey=ZQLCWPXBHUALQC-UHFFFAOYSA-N
• SMILES: Cc1ccc(C(=O)O)cc1O