N-Hydroxy-2-phenyl-acetamide

CAS: 5330-97-2

Ref. 3D-FH147414

Product Information

• Name: N-Hydroxy-2-phenyl-acetamide
• Brand: Biosynth
• Description: N-Hydroxy-2-phenyl-acetamide is a metalloprotease inhibitor that binds to the active site of the enzyme, thereby preventing it from binding with its natural substrate. This drug has been shown to inhibit the production of TNF-α in mice with autoimmune diseases and may be able to inhibit other proinflammatory mediators. N-Hydroxy-2-phenyl-acetamide has been shown to bind to a water molecule and an aliphatic hydrocarbon in order to form a hydrogen bond. This coordination complex inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen, elastin, and other proteins in the extracellular matrix. N-Hydroxy-2-phenyl-acetamide is not active against acid complexes or tnfα.

Chemical properties

• Molecular weight: 151.16 g/mol
• Formula: C₈H₉NO₂
• Purity: Min. 95%
• Color/Form: White Yellow Powder
• InChI: InChI=1S/C8H9NO2/c10-8(9-11)6-7-4-2-1-3-5-7/h1-5,11H,6H2,(H,9,10)
• InChI key: InChIKey=FPOQLQZHRCEVOT-UHFFFAOYSA-N
• SMILES: O=C(Cc1ccccc1)NO