1-Hydroxyethylidene-1,1-diphosphonic acid - 60% aqueous solution,~4.2mol/L

CAS: 2809-21-4

Ref. 3D-FH15419

Product Information

• Name: 1-Hydroxyethylidene-1,1-diphosphonic acid - 60% aqueous solution,~4.2mol/L
• Synonyms: Etidronic acidHEDP, (1-Hydroxyaethyliden)-Diphosphonsaeure, (1-Hydroxyethane-1,1-Diyl)Bis(Phosphonate), 1-Hydroxy-1,1-diphosphonoethane, 1000Sl, Ehdp, Ethidronate, Ethydronate, Etidronate, Etidronisaure, Hdepa, Hedp, Hedpa, Ksidifon, Oedf, Oedfk, Oedp, Wayplex, Xidifon, Xidiphone, Xydiphone, 1-Hydroxyethane-1,1-diphosphonic Acid, Phosphonic acid, (1-hydroxyethylidene)di-, 1-Hydroxyethylidene diphosphonic Acid, Hydroxyethylidenedi(phosphonic acid), disodium (1-hydroxyethane-1,1-diyl)bis[hydrogen(phosphonate)], 1-HYDROXYETHYLIDENEDI(PHOSPHONIC ACID), Phosphonic acid, (1-hydroxyethylidene)bis-, Hydroxyethylidine Diphosphonic Acid, Phosphonic acid, P,P′-(1-hydroxyethylidene)bis-, Etidronic acid, 1-hydroxy ethylene-1,1-diphosphonic acid, 1-Hydroxyethane-1,1-diphosphonic acid, 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid, Hydroxy Ethylidene-1,1-Diphosphonic Acid, HydroxyEthylidene Diphosphonic acid, P,P′-(1-Hydroxyethylidene)bis[phosphonic acid]

Description

1-Hydroxyethylidene-1,1-diphosphonic acid (HEDP) is a phosphonate that has been used as an inhibitor of the enzyme histone deacetylase. HEDP inhibits collagen production and root formation in cells. It also inhibits the uptake and mineralization of calcium by skin cells. HEDP has a strong inhibitory effect on protein synthesis, which may be due to its ability to bind to the active site of the enzyme protein kinase. In a short-term exposure experiment using an experimental model, HEDP caused significant cellular damage in the skin, which included increased cell death and decreased cell proliferation. HEDP also caused severe disruption of collagen fibers in the dermis layer of the skin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 206.03 g/mol
• Formula: C₂H₈O₇P₂
• Purity: (Titration) 59.0 To 65.0%
• Color/Form: White Clear Liquid
• InChI: InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)
• InChI key: InChIKey=DBVJJBKOTRCVKF-UHFFFAOYSA-N
• SMILES: CC(O)(P(=O)(O)O)P(=O)(O)O