alpha-Hydroxyhippuric acid

CAS: 16555-77-4

Ref. 3D-FH158929

Product Information

• Name: alpha-Hydroxyhippuric acid
• Synonyms: (2R)-hydroxy[(phenylcarbonyl)amino]ethanoate, (2S)-hydroxy[(phenylcarbonyl)amino]ethanoate, (Benzoylamino)(Hydroxy)Acetic Acid, 2-(Benzoylamino)-2-hydroxyacetic acid, 2-Benzamido-2-hydroxyacetic acid, 2-Benzamido-2-hydroxyaceticacid, 2-Hydroxy-2-(phenylformamido)acetic acid, Acetic acid, (benzoylamino)hydroxy-, Acetic acid, 2-(benzoylamino)-2-hydroxy-, Benzamidohydroxyacetic acid, Hippuric acid, α-hydroxy-, N-(2-hydroxybenzoyl)glycine, Salicylglycine, [(Benzoylamino)Oxy]Acetic Acid, alpha-Hydroxybenzoylglycine, {[(2-Hydroxyphenyl)Carbonyl]Amino}Acetate, Α-Hydroxyhippuric Acid
• CAS: 16555-77-4

Description

Alpha-hydroxyhippuric acid (AHA) is a metabolite of benzoic acid. It is the end product of the hydrolysis of the benzyl ester linkage in metoprolol succinate, and it can be detected in urine samples. AHA is a diagnostic marker for renal dysfunction and nephrology dialysis. The reaction mechanism for AHA formation is not known, but it may involve gamma-aminobutyric acid (GABA), which has been shown to inhibit carboxylesterase activity. In addition to being used as an indicator of renal function, AHA has also been used as a probe for gamma-aminobutyric acid receptors.
AHA has been shown to bind to thiophosphorylcholine (TPC) better than other amino acids, such as glycine or glutamic acid. This binding leads to conformational changes that are critical for TPC function and protein stability.

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.17 g/mol
• Formula: C₉H₉NO₄
• Purity: Min. 95%
• Color/Form: Powder