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4-Hydroxy-3-nitro-2(1H)-quinolinone
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4-Hydroxy-3-nitro-2(1H)-quinolinone

CAS: 15151-57-2

Ref. 3D-FH159597

5g
194.00 €
10g
310.00 €
25g
436.00 €
50g
646.00 €
100g
1,047.00 €
Estimated delivery in United States, on Thursday 23 Jan 2025

Product Information

Name:
4-Hydroxy-3-nitro-2(1H)-quinolinone
Synonyms:
  • 2(1H)-Quinolinone, 4-hydroxy-3-nitro-
  • 2,4-Quinolinediol, 3-nitro-
  • 2-hydroxy-3-nitroquinolin-4(1H)-one
  • 3-Nitro-2,4-Dihydroxyquinoline
  • 3-Nitro-2,4-quinolinediol
  • 3-Nitroquinoline-2,4-Diol
  • 3-Nitroquinoline-2,4-Diol, 4-Hydroxy-3-Nitro-1H-Quinolin-2-One
  • 4-hydroxy-3-nitro-2(1H)-Quinolinone
  • Timtec-Bb Sbb005381
  • 2,4-Dihydroxy-3-nitroquinoline
  • See more synonyms
Description:

4-Hydroxy-3-nitro-2(1H)-quinolinone is a quinoline derivative that has been shown to have anticancer activity against cancer cells. It can be used for the treatment of various types of cancer, including lung cancer, breast cancer, and colon cancer. This drug inhibits the growth of cancer cells by blocking the cycle at the G1 phase and inducing apoptosis. It also disrupts mitochondrial membrane potential, leading to an increase in reactive oxygen species and DNA damage. 4-Hydroxy-3-nitro-2(1H)-quinolinone is an epidermal growth factor receptor (EGFR) antagonist and blocks epidermal growth factor signaling through its inhibition of EGFR tyrosine kinase activity. It also downregulates TNFα expression in tumor cells by inhibiting NFκB activation.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
206.16 g/mol
Formula:
C9H6N2O4
Purity:
Min. 95%
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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