10-Hydroxycamptothecin

CAS: 19685-09-7

Ref. 3D-FH16009

Product Information

• Name: 10-Hydroxycamptothecin
• Brand: Biosynth
• Description: 10-Hydroxycamptothecin is an alkaloid, which is derived from the bark and stem of the Camptotheca acuminata tree, commonly known as the "Happy Tree." This compound is a potent topoisomerase I inhibitor. Its mode of action involves binding to the topoisomerase I-DNA complex, stabilizing it and thus preventing the re-ligation of DNA single-strand breaks. This interruption in the DNA replication process leads to DNA damage, ultimately triggering apoptosis in rapidly dividing cells.

Chemical properties

• Molecular weight: 364.35 g/mol
• Formula: C₂₀H₁₆N₂O₅
• Purity: Min. 95%
• Color/Form: Powder