6b-Hydroxycortisol
CAS: 3078-34-0
Ref. 3D-FH167095
1mg | 248.00 € | ||
2mg | 364.00 € | ||
5mg | 647.00 € | ||
10mg | 986.00 € | ||
25mg | 1,884.00 € |
Product Information
- 4-Pregnen-6b,11b,17,21-tetrol-3,20-dione
6b-Hydroxycortisol is a metabolite of cortisol and an intermediate in the synthesis of aldosterone. It is produced by the enzyme 11-beta hydroxysteroid dehydrogenase type 1 (11βHSD1). 6b-Hydroxydexosterone has been shown to be present at physiological levels in the blood, and it is excreted in urine at concentrations that are proportional to its production rate. The concentration-time curve for 6b-hydroxydexosterone is similar to that for cortisol, with a peak at about 2 hours after administration. Plasma levels of 6b-hydroxydexosterone are increased in patients with bowel disease, and mouse monoclonal antibody against this metabolite has been shown to reduce inflammation in mice with bowel disease. This metabolite also has a role in regulating enzyme activities such as those associated with congestive heart failure or drug interactions. The analytical method for 6b-hydroxydexosterone is based
Chemical properties
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