Carbidopa impurity F

CAS: 1458640-32-8

Ref. 3D-FH177492

Product Information

• Name: Carbidopa impurity F
• Synonyms: (αS)-α-Hydrazinyl-3,4-dihydroxy-α-methylbenzenepropanoic acid ethyl esterCarbidopa EP impurity F
• Brand: Biosynth
• Description: Carbidopa is an impurity of the drug L-DOPA, which is used as a treatment for Parkinson's disease. Carbidopa is a prodrug that is converted to L-DOPA by decarboxylase, an enzyme in the body. The conversion process can be inhibited by the presence of carbidopa impurity F (CIF), which binds to carboxamides and forms a stable complex with them. This prevents CIF from binding to decarboxylase and blocking its ability to convert carbidopa into L-DOPA. CIF has been shown to have anti-parkinsonian effects by reducing the severity of symptoms associated with Parkinson's disease such as muscular rigidity and tremors.

Chemical properties

• Molecular weight: 254.28 g/mol
• Formula: C₁₂H₁₈N₂O₄
• Purity: Min. 95%
• Color/Form: Powder