Helenalin

CAS: 6754-13-8

Ref. 3D-FH177939

Product Information

• Name: Helenalin
• Synonyms: (3aS)-3,3aalpha,4alpha,4a,7aalpha,8,9,9aalpha-Octahydro-4-hydroxy-4abeta,8 alpha-dimethyl-3-methyleneazuleno(6,5-b)-furan-2,5-dione, (3aS,4S,4aR,7aR,8R,9aR)-3,3a,4,4a,7a,8,9,9a-Octahydro-4-hydroxy-4a,8-dimethyl-3-methyleneazuleno[6,5-b]furan-2,5-dione, (3aS,4S,4aR,7aR,8R,9aR)-4-hydroxy-4a,8-dimethyl-3-methylidene-3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione, 6alpha,8beta-Dihydroxy-4-oxoambrosa-2,11(13)-dien-12-oic acid 12,8-lactone, Ambrosa-2,11(13)-dien-12-oic acid, 6-alpha,8-beta-dihydroxy-4-oxo-, 12,8-lactone, Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone, Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone (8CI), Ambrosa-2,11(13)-dien-12-oic acid, 6α,8β-dihydroxy-4-oxo-, 12,8-lactone, Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-, Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))- (9CI), Azuleno[6,5-b]furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS,4S,4aR,7aR,8R,9aR)-, Azuleno[6,5-b]furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, [3aS-(3aα,4α,4aβ,7aα,8α,9aα)]-, Brn 0028081, Helenalin A, Hsdb 3490, Nsc 85236, Pf 56

Description

Helenalin is a natural compound that belongs to the group of nonsteroidal anti-inflammatory drugs. It has been shown to inhibit 3t3-l1 preadipocytes differentiation and promote apoptosis by inhibiting the phosphorylation of c-jun, as well as decreasing the expression of Mcl-1 protein. Helenalin also inhibits NF-κB binding activity and suppresses the transcriptional factor nuclear factor kappa B (NF-κB) in a dose dependent manner. The antitumor activity of helenalin has been shown to be due to its ability to inhibit cyclin D2 expression, which prevents tumor cell proliferation.

• Brand: Biosynth

Chemical properties

• Purity: Min. 95%