Homotaurine

CAS: 3687-18-1

Ref. 3D-FH23857

Product Information

• Name: Homotaurine
• Synonyms: 3-Amino-1-propanesulfonic acid3-Aminopropiosulfonic acid3-Sulfopropylamine, 1-Propanesulfonic acid, 3-amino-, 3 Aps, 3-Amino-1-propanesulfonate, 3-Aminopropane-1-Sulphonic Acid, 3-Aminopropanesulfonic acid, 3-Aminopropiosulfonic acid, 3-Azaniumylpropane-1-sulfonate, 3-Sulfopropylamine, Alzhemed, NSC 77071, Nc 758, Tramiprosate, γ-Aminopropylsulfonic acid, 3-Amino-1-propanesulfonic acid

Description

Homotaurine is a secretase inhibitor that has been shown to have anti-Alzheimer's disease effects in vivo. It has been shown to increase serum prolactin levels and improve locomotor activity in mice. Homotaurine also has the ability to inhibit the production of glutamate, an excitatory neurotransmitter, through its inhibition of N-acetyl-L-aspartate (NAA) synthesis. This drug is also an oral prodrug, which can be activated by hydrolysis in the gastrointestinal tract to release homotaurine. The reaction mechanism for this compound is not yet clear but it may involve natural compounds such as choline or acetylcholine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 139.17 g/mol
• Formula: C₃H₉NO₃S
• Purity: (Titration) Min 96%
• Color/Form: White Powder
• InChI: InChI=1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
• InChI key: InChIKey=SNKZJIOFVMKAOJ-UHFFFAOYSA-N
• SMILES: NCCCS(=O)(=O)O