Hydralazine hydrochloride

CAS: 304-20-1

Ref. 3D-FH23871

Product Information

• Name: Hydralazine hydrochloride
• Synonyms: 1-Hydrazinylphthalazine hydrochloride1(2H)-Phthalazinone hydrazone hydrochloride1-Phthalazinylhydrazine hydrochloride, (Phthalazin-1-yl)hydrazine hydrochloride, 1(2H)-Phthalazinone hydrazone, 1(2H)-Phthalazinone, hydrazone, monohydrochloride, 1-Hydrazinophthalazine hydrochloride, 1-Hydrazinophthalazine monohydrochloride, 1-Hydrazinylphthalazine, 1-Hydrazinylphthalazine Hydrochloride (1:1), 1-Hydrazinylphthalazine hydrochloride, Apresoline hydrochloride, Apulon, Hydralazine chloride, Hydralazine hcl, Hydralazine monohydrochloride, Lopres, Phthalazine, 1-hydrazino-, monohydrochloride, Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)

Description

Hydralazine hydrochloride is a drug used to treat high blood pressure. It is an inhibitor of the enzyme phosphodiesterase, which leads to increased levels of cAMP and vasodilation in the lungs. Hydralazine hydrochloride has been shown to induce renal injury, specifically by inhibiting the synthesis of prostaglandins that protect the kidneys from damage. This drug can also cause cardiac effects such as tachycardia and arrhythmias. Hydralazine hydrochloride interacts with other drugs, including Candesartan cilexetil and other drugs that inhibit phosphodiesterase, leading to an increase in blood pressure. Hydralazine hydrochloride binds to guanine nucleotide-binding proteins (G proteins) on neural cells and increases the rate constant for G protein activation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 196.64 g/mol
• Formula: C₈H₉ClN₄
• Purity: Min. 95%
• Color/Form: White Powder