6'-Hydroxy buspirone

CAS: 125481-61-0

Ref. 3D-FH23929

Product Information

• Name: 6'-Hydroxy buspirone
• Synonyms: 6-Hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione6'-HydroxybuspironeBMS 528215
• Brand: Biosynth
• Description: 6'-Hydroxy buspirone is a prodrug of buspirone, which is an antidepressant drug. It has been shown to have a matrix effect and profile similar to that of buspirone in humans. The compound has been found to be effective in the treatment of depression. 6'-Hydroxy buspirone has been shown to inhibit the dopamine D3 receptor with a potency similar to that of buspirone and other dopamine antagonists. This inhibition may be responsible for the antidepressant effects observed in clinical trials. The compound also inhibits serotonin reuptake, which may account for its antidepressant activity. 6'-Hydroxy buspirone is not metabolized by cytochrome P450 enzymes, making it more selective than some other drugs that are metabolized by this enzyme system.

Chemical properties

• Molecular weight: 401.5 g/mol
• Formula: C₂₁H₃₁N₅O₃
• Purity: Min. 95%
• Color/Form: Powder