Hydroxy celecoxib

CAS: 170571-00-3

Ref. 3D-FH23937

Product Information

• Name: Hydroxy celecoxib
• Synonyms: 4-[5-[4-(Hydroxymethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

Description

Celecoxib is a nonsteroidal anti-inflammatory drug that has been shown to be effective in the treatment of pain and inflammation. It belongs to the pyrazole ring family, and is also known as a COX-2 inhibitor. The efficacy of celecoxib can be determined using a pharmacokinetics study of serum samples collected from human volunteers. The sample preparation involves a high-performance liquid chromatography (LC) with mass spectrometry detection method, which is used to measure concentrations of the drug in blood plasma over time. This analytical method is used for kinetic data analysis, and it can be used to identify drug interactions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 397.37 g/mol
• Formula: C₁₇H₁₄F₃N₃O₃S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C17H14F3N3O3S/c18-17(19,20)16-9-15(12-3-1-11(10-24)2-4-12)23(22-16)13-5-7-14(8-6-13)27(21,25)26/h1-9,24H,10H2,(H2,21,25,26)
• InChI key: InChIKey=ICRSYPPLGADZKA-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(CO)cc2)cc1