22α-Hydroxy cholesterol
CAS:
Ref. 3D-FH23942
1mg
341.00€
2mg
486.00€
5mg
729.00€
10mg
1,085.00€
25mg
2,112.00€
Product Information
Name:22α-Hydroxy cholesterol
Controlled Product
Synonyms:
- (3β,22R)-Cholest-5-ene-3,22-diol(20S,22R)-Cholest-5-ene-3b,22-diol(22R)-22-Hydroxycholesterol
Brand:Biosynth
Description:22a-Hydroxycholesterol is a naturally occurring, oxygenated cholesterol metabolite. It binds to the transcriptional coactivator retinoid X receptor (RXR) and inhibits the activity of certain liver enzymes. 22a-Hydroxycholesterol has been shown to have toxic effects on mouse tumors and to inhibit the production of ATP in vitro. 22a-Hydoxycholesterol also inhibits the function of ATP binding cassette (ABC) transporter proteins, which are involved in cholesterol transport from cells. The long-term toxicity of 22a-hydroxycholesterol is not well understood, although it has been shown that this metabolite can induce autoimmune diseases in rats.
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Chemical properties
Molecular weight:402.65 g/mol
Formula:C27H46O2
Purity:Min. 95%
Technical inquiry about: 22α-Hydroxy cholesterol
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