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22α-Hydroxy cholesterol
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22α-Hydroxy cholesterol

CAS: 17954-98-2

Ref. 3D-FH23942

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Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
22α-Hydroxy cholesterol
Controlled Product
Synonyms:
  • (3β,22R)-Cholest-5-ene-3,22-diol(20S,22R)-Cholest-5-ene-3b,22-diol(22R)-22-Hydroxycholesterol
Description:

22a-Hydroxycholesterol is a naturally occurring, oxygenated cholesterol metabolite. It binds to the transcriptional coactivator retinoid X receptor (RXR) and inhibits the activity of certain liver enzymes. 22a-Hydroxycholesterol has been shown to have toxic effects on mouse tumors and to inhibit the production of ATP in vitro. 22a-Hydoxycholesterol also inhibits the function of ATP binding cassette (ABC) transporter proteins, which are involved in cholesterol transport from cells. The long-term toxicity of 22a-hydroxycholesterol is not well understood, although it has been shown that this metabolite can induce autoimmune diseases in rats.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
402.65 g/mol
Formula:
C27H46O2
Purity:
Min. 95%
MDL:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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