22β-Hydroxy cholesterol

CAS: 22348-64-7

Ref. 3D-FH23943

Product Information

• Name: 22β-Hydroxy cholesterol
• Synonyms: (3β,22S)-Cholest-5-ene-3,22-diol(20S,22S)-Cholest-5-ene-3β,22-diol(22S)-22-Hydroxycholesterol
• Brand: Biosynth
• Description: 22-Hydroxycholesterol is a product of cholesterol synthesis, which is formed by the side-chain cleavage of cholesterol. This compound has been shown to inhibit cholesterol acyltransferase and to be cytotoxic in vitro. 22-Hydroxycholesterol has also been shown to have an inhibitory effect on protein synthesis and on the activity of forskolin, an activator of adenylate cyclase that is involved in the regulation of cellular levels of cAMP. The antioxidant properties of 22-hydoxycholesterol may be due to its chemical structure, which includes a hydroxyl group. This compound also shows an insulin-sensitizing effect in mice fed a high fat diet.

Chemical properties

• Molecular weight: 402.65 g/mol
• Formula: C₂₇H₄₆O₂
• Purity: Min. 95%