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4-Hydroxy duloxetine
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4-Hydroxy duloxetine

CAS: 662149-13-5

Ref. 3D-FH23990

1mg
542.00 €
2mg
947.00 €
5mg
1,985.00 €
10mg
3,241.00 €
Estimated delivery in United States, on Thursday 19 Dec 2024

Product Information

Name:
4-Hydroxy duloxetine
Synonyms:
  • 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthalenol
Description:

Duloxetine is a potent inhibitor of cytochrome P450, which is an enzyme that metabolizes many drugs. Duloxetine inhibits the glucuronidation of 4-hydroxy duloxetine, leading to increased levels in the blood. Duloxetine has been shown to be effective in the treatment of diabetic neuropathy, with statistically significant improvements in symptoms and nerve conduction velocity. The pharmacokinetics of duloxetine has been studied in both rats and humans. In rats, duloxetine was found to have a large volume of distribution and a long half-life, suggesting that it is not well absorbed into the blood stream. In humans, duloxetine is metabolized by CYP2D6 and CYP3A4 enzymes. It has been shown to interact with other drugs such as warfarin, tizanidine, tramadol, and fluconazole.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
313.42 g/mol
Formula:
C18H19NO2S
Purity:
Min. 95%
Color/Form:
Beige To Light Brown Solid
InChI:
InChI=1S/C18H19NO2S/c1-19-11-10-17(18-7-4-12-22-18)21-16-9-8-15(20)13-5-2-3-6-14(13)16/h2-9,12,17,19-20H,10-11H2,1H3/t17-/m0/s1
InChI key:
InChIKey=DRRXQCXSBONKPD-KRWDZBQOSA-N
SMILES:
CNCC[C@H](Oc1ccc(O)c2ccccc12)c1cccs1
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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