2-Hydroxyhippuric acid

CAS: 487-54-7

Ref. 3D-FH24019

Product Information

• Name: 2-Hydroxyhippuric acid
• Synonyms: N-(2-Hydroxybenzoyl)glycineo-Hydroxy-hippuric acidSalicyluric acid, (2-Hydroxybenzoyl)glycine, (2R)-hydroxy[(phenylcarbonyl)amino]ethanoate, (2S)-hydroxy[(phenylcarbonyl)amino]ethanoate, (Benzoylamino)(Hydroxy)Acetic Acid, 2-(2-Hydroxybenzamido)acetic acid, 2-[(2-Hydroxyphenyl)formamido]acetic acid, Glycine, N-(2-hydroxybenzoyl)-, Hippuric acid, o-hydroxy-, N-(2-hydroxybenzoyl)glycine, N-(o-Hydroxybenzoyl)glycine, N-Salicyloylglycine, NSC 524135, Salicylglycine, Salicyloylglycine, Salicyluric acid, [(Benzoylamino)Oxy]Acetic Acid, alpha-Hydroxybenzoylglycine, alpha-Hydroxyhippuric acid, o-Hydroxyhippuric acid, {[(2-Hydroxyphenyl)Carbonyl]Amino}Acetate, Α-Hydroxyhippuric Acid

Description

2-Hydroxyhippuric acid (2HPA) is a metabolite of salicylic acid. 2HPA is used to measure the concentration of salicylic acid in urine, which can be used as a biomarker for disease activity. When 2HPA is present in the urine, it indicates that the body has been exposed to salicylic acid. The concentration of 2HPA in urine correlates with the amount of salicylic acid taken orally and excreted by the kidneys. The analytical method for determining 2HPA in urine involves measuring the concentration of 2HPA and its derivatives with high pressure liquid chromatography or gas chromatography-mass spectrometry. Some biological samples that can be tested include blood, serum, plasma, saliva, sweat, or hair. Pharmacological agents that may affect 2HPA levels include other drugs such as nonsteroidal anti-inflammatory drugs (NSAIDs) or aspirin. The model system for this metabolite is human

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.17 g/mol
• Formula: C₉H₉NO₄
• Purity: Min. 94 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)
• InChI key: InChIKey=ONJSZLXSECQROL-UHFFFAOYSA-N
• SMILES: O=C(O)CNC(=O)c1ccccc1O