2-Hydroxy nicotinic acid

CAS: 609-71-2

Ref. 3D-FH24065

Product Information

• Name: 2-Hydroxy nicotinic acid
• Synonyms: 1,2-Dihydro-2-oxo-3-pyridinecarboxylic acid1,2-Dihydro-2-oxonicotinic acid 1,2-dihydro-2-oxo-3-pyridinecarboxylic acid1,2-Dihydro- 2-oxonicotinic acid, 1,2-Dihydro-2-oxo-3-pyridinecarboxylic acid, 1,2-Dihydro-2-oxonicotinic acid, 2-Hydroxy-3-Pyridine Carboxylic acid, 2-Hydroxy-3-carboxypyridine, 2-Hydroxypyridine-3-carboxylic acid, 2-Oxo-1,2-Dihydropyridine-3-Carboxylate, 2-Oxo-1,2-Dihydropyridine-3-Carboxylic Acid, 2-Oxo-1H-pyridine-3-carboxylic acid, 2-Oxopyridine-3-carboxylic acid, 3-Carboxy-2-pyridone, 3-Pyridinecarboxylic acid, 1,2-dihydro-2-oxo-, NSC 226152, Nicotinic acid, 1,2-dihydro-2-oxo-, 2-Hydroxynicotinic acid

Description

2-Hydroxy nicotinic acid is a carboxylate with a hydroxyl group. The compound has been shown to produce light emission in the presence of ultraviolet radiation and picolinic acid, which is an electron acceptor. This reaction is catalyzed by NADH oxidase and requires the presence of molecular oxygen. 2-Hydroxy nicotinic acid has also been shown to inhibit the activity of enzymes that are involved in the synthesis of nicotinamide adenine dinucleotide (NAD), including nicotinamide phosphoribosyltransferase (NAMPT), which produces NAD from niacinamide, and nicotinate phosphoribosyltransferase (NPT). The optimum concentration for this compound is between 1-2 mM. 2-Hydroxy nicotinic acid can be synthesized from natural compounds such as vitamin B3 or nicotinamide riboside through hydrolysis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 139.11 g/mol
• Formula: C₆H₅NO₃
• Purity: Min. 95%
• Color/Form: Powder