DL-4-Hydroxy-2-ketoglutarate dilithium salt

CAS: 1187-99-1

Ref. 3D-FH24198

Product Information

• Name: DL-4-Hydroxy-2-ketoglutarate dilithium salt
• Synonyms: 2-Hydroxy-4-oxopentanedioic acid
• Brand: Biosynth
• Description: DL-4-Hydroxy-2-ketoglutarate dilithium salt (DL4KG) is a lysine analogue that is used as a substrate for the enzyme aldolase. DL4KG has a hydroxyl group, which can react with the amino group of lysine residues on proteins to produce an unstable intermediate. This process eventually leads to the production of glutamate and glyceraldehyde 3-phosphate, which are needed in the synthesis of ATP. DL4KG has been shown to be an inhibitor of bacterial enzymes such as glutamate dehydrogenase, which catalyzes the conversion of L-glutamic acid to L-glutamine. Inhibition by DL4KG has been demonstrated in vitro at concentrations between 2 and 10 mM.

Chemical properties

• Molecular weight: 173.96 g/mol
• Formula: C₅H₄O₆Li₂
• Purity: 90%Min
• Color/Form: White to off-white solid.