2'-Hydroxy-4',5'-dimethylacetophenone

CAS: 36436-65-4

Ref. 3D-FH24249

Product Information

• Name: 2'-Hydroxy-4',5'-dimethylacetophenone
• Synonyms: 1-(2-Hydroxy-4,5-dimethylphenyl)ethanone2-Acetyl-4,5-dimethylphenol4',5'-Dimethyl-2'-hydroxyacetophenone, 1-(2-Hydroxy-4,5-Dimethylphenyl)Ethanone, 1-(2-Hydroxy-4,5-dimethylphenyl)ethan-1-one, 1-(4,5-Dimethyl-2-hydroxyphenyl)ethanone, 2-Acetyl-4,5-dimethylphenol, 2′-Hydroxy-4′,5′-dimethylacetophenone, 4,5-Dimethyl-2-hydroxyacetophenone, Acetophenone, 2′-hydroxy-4′,5′-dimethyl-, Ethanone, 1-(2-hydroxy-4,5-dimethylphenyl)-
• CAS: 36436-65-4

Description

2'-Hydroxy-4',5'-dimethylacetophenone is a chalcone that is structurally similar to the catecholamines. It has been shown to inhibit bacterial growth in vitro and in vivo and to be active against both Gram-positive and Gram-negative bacteria. This compound also has antiviral activity, inhibiting the replication of herpes simplex virus type 1 (HSV-1) in cell culture. 2'-Hydroxy-4',5'-dimethylacetophenone also has antibacterial activity against Trichophyton mentagrophytes and Melaleuca alternifolia, an Australian tree that produces a range of bioactive compounds with antimicrobial properties. 2'-Hydroxy-4',5'-dimethylacetophenone binds to the enzyme phosphodiesterase, blocking the conversion of cyclic adenosine monophosphate (cAMP) into its inactive form cAMP hydrolysis product (cAMP). Inhibition of this enzyme

• Brand: Biosynth

Chemical properties

• Molecular weight: 164.2 g/mol
• Formula: C₁₀H₁₂O₂
• Purity: Min. 95%
• Color/Form: Off-White To Yellow Solid
• InChI: InChI=1S/C10H12O2/c1-6-4-9(8(3)11)10(12)5-7(6)2/h4-5,12H,1-3H3
• InChI key: InChIKey=YXVSURZEXVMUAM-UHFFFAOYSA-N
• SMILES: CC(=O)c1cc(C)c(C)cc1O