Ferulic acid

CAS: 537-73-5

Ref. 3D-FH24260

Product Information

• Name: Ferulic acid
• Synonyms: (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid, (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoate, (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid, 2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)-, 3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid, 4-Methoxycaffeic acid, 4-O-Methylcaffeic acid, Cinnamic acid, 3-hydroxy-4-methoxy-, Hesperetic acid, Isoferulic acid, NSC 51987

Description

Ferulic acid is a plant polyphenol that has been shown to induce apoptosis in human leukemia cells and inhibit the production of tumor necrosis factor-α (TNF-α), thereby improving glucose tolerance. Ferulic acid inhibits the mitochondrial membrane potential by binding to the Mcl-1 protein and inducing its degradation, leading to anion radical scavenging. This compound also has significant cytotoxicity in a model system and has been shown to have hypoglycemic effects in animal studies. Ferulic acid also induces cell cycle arrest by inhibiting the expression of cyclin D1, which is involved in regulating the G1 phase of the cell cycle.

• Brand: Biosynth

Chemical properties

• Molecular weight: 194.18 g/mol
• Formula: C₁₀H₁₀O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H10O4/c1-14-9-4-2-7(6-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+
• InChI key: InChIKey=QURCVMIEKCOAJU-HWKANZROSA-N
• SMILES: COc1ccc(/C=C/C(=O)O)cc1O