(S)-2-Hydroxy-4-phenylbutyric acid ethyl ester

CAS: 125639-64-7

Ref. 3D-FH24270

Product Information

• Name: (S)-2-Hydroxy-4-phenylbutyric acid ethyl ester
• Synonyms: (a-S)-a-Hydroxybenzenebutanoic Acid Ethyl Ester, 2-(S)-Hydroxy-4-Phenyl-BUTYRIC ACID, ETHYL ESTER, S-(+)-ETHYL 2-Hydroxy-4-phenylbutyrate, Ethyl (S)-2-hydroxy-4-phenybutyrate, ethyl (2S)-2-hydroxy-4-phenylbutanoate, Ethyl(S)-2-hydroxy-4-phenylbutanoate

Description

(S)-2-Hydroxy-4-phenylbutyric acid ethyl ester is a chiral ester compound that is synthesized from formate, the enzyme formate dehydrogenase, and an enantiomerically pure racemic form of (S)-2-hydroxy-4-phenylbutyric acid. This compound has been shown to inhibit candida parapsilosis, which is a fungus that causes oral thrush. The synthesis of this compound may be achieved by reacting methyl acetate with sodium methoxide in methanol at 0°C to produce the methyl ester. This reaction produces two stereoisomers: one (R) and one (S). The racemic mixture can be resolved into its constituent enantiomers by either crystallization or chromatography. Crystallization will yield the (R) enantiomer while chromatography will yield the (S) enantiomer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 208.25 g/mol
• Formula: C₁₂H₁₆O₃
• Purity: Min. 95%