5-Hydroxyisoquinoline

CAS: 2439-04-5

Ref. 3D-FH24373

Product Information

• Name: 5-Hydroxyisoquinoline
• Synonyms: 5-IsoquinolinolNSC 51787, 5-Hydroxyisoquin dine, 5-Hydroxyisoquinoline90%, 5-Isoquinolinol, Isoquinolin-5-Ol, NSC 51787

Description

5-Hydroxyisoquinoline is a quinoline derivative that is synthesized from aziridine. It has been shown to be a potent insulin sensitizing agent in mice with type 2 diabetes mellitus. 5-Hydroxyisoquinoline has been shown to inhibit the activity of purified enzymes preparations and show high selectivity for chloride channels, which are responsible for the transport of chloride ions across cell membranes. This inhibition leads to an influx of protons into the cell, which may lead to a change in the redox potential and changes in the molecular structure of the molecule. The reaction mechanism involves substitution at position 5 of the isoquinoline ring by hydroxy groups (OH).

• Brand: Biosynth

Chemical properties

• Molecular weight: 145.16 g/mol
• Formula: C₉H₇NO
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C9H7NO/c11-9-3-1-2-7-6-10-5-4-8(7)9/h1-6,11H
• InChI key: InChIKey=CSNXUYRHPXGSJD-UHFFFAOYSA-N
• SMILES: Oc1cccc2cnccc12