3-Hydroxymandelic acid

CAS: 17119-15-2

Ref. 3D-FH24383

Product Information

• Name: 3-Hydroxymandelic acid
• Synonyms: (+/-)-m-Hydroxymandelic acidDL-3-Hydroxymandelic acida,3-Dihydroxy-benzeneacetic acid, (±)-m-Hydroxymandelic acid, 2-Hydroxy-2-(3-Hydroxyphenyl)Acetic Acid, 3-Hydroxyphenylglycolic acid, <span class="text-smallcaps">DL</span>-3-Hydroxymandelic acid, Benzeneacetic acid, α,3-dihydroxy-, Hydroxy(3-Hydroxyphenyl)Acetic Acid, Mandelic acid, m-hydroxy-, alpha,3-Dihydroxybenzeneacetic acid, α,3-Dihydroxybenzeneacetic acid

Description

3-Hydroxymandelic acid is a metabolite of mandelic acid and has been found to have cytostatic effects in human cells. The concentration-time curve for 3-hydroxymandelic acid displays a single-dose pharmacokinetics. It has been shown to inhibit the nuclear factor kappa-light-chain enhancer (NFκB) pathway, which is involved in the regulation of cell proliferation, differentiation, and apoptosis. 3-Hydroxymandelic acid also inhibits energy metabolism by reducing mitochondrial respiration. This compound binds to plasma proteins and is excreted through urine as well as being oxidized by hepatic cytochrome P450 enzymes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 168.15 g/mol
• Formula: C₈H₈O₄
• Purity: Min. 95%
• InChI: InChI=1S/C8H8O4/c9-6-3-1-2-5(4-6)7(10)8(11)12/h1-4,7,9-10H,(H,11,12)
• InChI key: InChIKey=OLSDAJRAVOVKLG-UHFFFAOYSA-N
• SMILES: O=C(O)C(O)c1cccc(O)c1