2-Hydroxymethyl olanzapine

CAS: 174756-45-7

Ref. 3D-FH24394

Product Information

• Name: 2-Hydroxymethyl olanzapine
• Synonyms: 4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanolLY 290411, 10H-Thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-(4-methyl-1-piperazinyl)-, 2-Hydroxymethyl Olanzapine-d3, 4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-[4-(Methyl-d3)-1-piperazinyl]-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol, Ly 290411, [4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol

Description

2-Hydroxymethyl olanzapine is an atypical antipsychotic drug that can be used to treat schizophrenia and other psychotic disorders. The drug is metabolized in the liver and has a linear response in plasma concentrations. It has been shown to have high plasma levels in humans, with a wide range of therapeutic effects. 2-Hydroxymethyl olanzapine has been found to be more effective for women than men, as well as for patients suffering from hyperactivity and psychosis. This drug should not be administered to patients who are experiencing symptoms of schizophrenia or other psychotic disorders. 2-Hydroxymethyl olanzapine is extracted from human liver cells by using organic solvents such as chloroform or dichloromethane. It can also be synthesized from 2-chloroethanol and benzaldehyde through a process of reductive amination.

• Brand: Biosynth

Chemical properties

• Molecular weight: 328.43 g/mol
• Formula: C₁₇H₂₀N₄OS
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C17H20N4OS/c1-20-6-8-21(9-7-20)16-13-10-12(11-22)23-17(13)19-15-5-3-2-4-14(15)18-16/h2-5,10,19,22H,6-9,11H2,1H3
• InChI key: InChIKey=FPDIERBPQFAFSI-UHFFFAOYSA-N
• SMILES: CN1CCN(C2=Nc3ccccc3Nc3sc(CO)cc32)CC1