3-(4-Hydroxyphenyl)propionitrile

CAS: 17362-17-3

Ref. 3D-FH24473

Product Information

• Name: 3-(4-Hydroxyphenyl)propionitrile
• Synonyms: p-(2-Cyanoethyl)phenol4-Hydroxyhydrocinnamonitrile4-Hydroxybenzenepropanenitrile, 3-(4-Hydroxyphenyl)Propanenitrile, 3-(P-Hydroxyphenyl) Propionitrile, 4-(2-Cyanoethyl)phenol, 4-Hydroxybenzenepropanenitrile, 4-Hydroxyhydrocinnamonitrile, 4-Hydroxyphenylpropionitrile, Benzenepropanenitrile, 4-hydroxy-, Hydrocinnamonitrile, p-hydroxy-, NSC 163340, beta-(4-Hydroxyphenyl)propionitrile, p-(2-Cyanoethyl)phenol, β-(4-Hydroxyphenyl)propionitrile, β-(p-Hydroxyphenyl)propionitrile

Description

3-(4-Hydroxyphenyl)propionitrile (3HP) is a natural product that has been found to inhibit the activity of the enzyme parathyroid adenomatosis, which leads to an accumulation of calcium in the blood. 3HP is hydrolyzed by glucobarbarin, a cytochrome P450 enzyme in liver cells, to phenylpropionic acid and 4-hydroxybenzoic acid. The subsequent conjugation of these metabolites with glutathione results in the formation of 3-hydroxy-4-phenylpropionic acid, which inhibits the activity of parathyroid adenomatosis by increasing its degradation rate.

• Brand: Biosynth

Chemical properties

• Molecular weight: 147.17 g/mol
• Formula: C₉H₉NO
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/H3N/h1H3
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#CCCc1ccc(O)cc1