Product Information
Name:5-Hydroxypyrazine-2-carboxylic acid
Synonyms:
- 4,5-Dihydro-5-oxopyrazinecarboxylic acid5-Hydroxypyrazinecarboxylic acid5-Hydroxypyrazinoic acid
Brand:Biosynth
Description:5-Hydroxypyrazine-2-carboxylic acid is a drug that inhibits the activation of proteins involved in cell signaling pathways. It has been shown to have an inhibitory effect on the activation of protein kinase C, which plays a key role in the proliferation and differentiation of cells. 5-Hydroxypyrazine-2-carboxylic acid also inhibits sorafenib, a drug used for the treatment of cancer. Sorafenib is metabolized in rats by cytochrome P450 (CYP) enzymes, which are found in human liver tissue as well. The metabolism rate of sorafenib can be reduced by coadministration with caffeine or other substances that induce CYP activity. 5-Hydroxypyrazine-2-carboxylic acid is not active against pyrazinoic acid and pyrazine-2 carboxylate, which are metabolites produced by CYP enzymes.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:140.1 g/mol
Formula:C5H4N2O3
Purity:Min. 98 Area-%
Color/Form:Brown Powder
InChI:InChI=1S/C5H4N2O3/c8-4-2-6-3(1-7-4)5(9)10/h1-2H,(H,7,8)(H,9,10)
InChI key:InChIKey=CGQFCIHUUCMACC-UHFFFAOYSA-N
SMILES:O=C(O)c1c[nH]c(=O)cn1
Technical inquiry about: 5-Hydroxypyrazine-2-carboxylic acid
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