7-Hydroxyquinoline-(1H)-2-one

CAS: 70500-72-0

Ref. 3D-FH24500

Product Information

• Name: 7-Hydroxyquinoline-(1H)-2-one
• Synonyms: 7-Hydroxy-2(1H)-quinolinone7-Hydroxycarbostyril, 2(1H)-Quindinone,3,4-dohydro-7Hydroxy, 2(1H)-Quinolinone, 7-hydroxy-, 2,7-Dihydroxyquinoline, 3,4-Dihydro-7-Hydroxy-2(1H)-Quinlinone, 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone, 3,4-Dihydro-7-hydroxycarbostyril, 7-Hydroxy carbostyril, 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone, 7-Hydroxy-1,2-Dihydroquinolin-2-One, 7-Hydroxy-2-(1H)-quinolinone, 7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone, 7-Hydroxy-3,4-Dihydro-2-(1H)-Quinoline, 7-Hydroxy-3,4-dihydro-1H-quinolin-2-one, 7-Hydroxy-3,4-dihydrocarbostyril, 7-Hydroxy-3,4-dihydroquinolone, 7-Hydroxycarbostyril, 7-Hydroxyquinolin-2(1H)-One, 7-hydroxy-1H-quinolin-2-one, 7-hydroxy-3,4-dihydroquinolin-2(1H)-one

Description

7-Hydroxyquinoline-(1H)-2-one is a quinoline derivative that binds to epidermal growth factor (EGF) receptors. It has been shown to inhibit the chloride current in neurons, which may be due to its ability to bind to the dopamine receptors in these cells. 7-Hydroxyquinoline-(1H)-2-one also inhibits DNA and protein synthesis by binding to nucleophilic nitrogen atoms and protonated nitrogen atoms, respectively. It has been shown to have an inhibitory effect on cancer cell growth in control experiments. This drug is not active against normal cells because it does not bind well to them. 7-Hydroxyquinoline-(1H)-2-one binds with high affinity to piperazine and this interaction can be used as a fluorescent probe for the presence of quinoline derivatives.

• Brand: Biosynth

Chemical properties

• Molecular weight: 161.16 g/mol
• Formula: C₉H₇NO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C9H7NO2/c11-7-3-1-6-2-4-9(12)10-8(6)5-7/h1-5,11H,(H,10,12)
• InChI key: InChIKey=DBSPUDKBNOZFMX-UHFFFAOYSA-N
• SMILES: O=c1ccc2ccc(O)cc2[nH]1