2-Hydrazinylpyridine

CAS: 4930-98-7

Ref. 3D-FH32836

Product Information

• Name: 2-Hydrazinylpyridine
• Synonyms: (2E)-2(1H)-Pyridinone hydrazone, 2(1H)-Pyridinone, hydrazone, 2-Hydrazinylpyrimidine, 2-Pyridinylhydrazine, 2-Pyridylhydrazine, Hydrazine, 2-pyridinyl-, NSC 76877, Pyridin-2-Yl-Hydrazine, Pyridine, 2-hydrazino-, Pyridine, 2-hydrazinyl-, α-Pyridylhydrazine

Description

2-Hydrazinylpyridine (2HNP) is a compound that has been used to detect the presence of hydrogen bonds in biological samples. It reacts with the nitrogen atoms in a sample to form an adduct and then reacts with human serum to form a fluorescent product. This reaction has been shown to be sensitive enough for detection of hydrogen bonding interactions in biological samples. 2HNP has also been shown to react with proteins, such as cyclic peptides, which are targets for toxicological studies. 2HNP reacts with the nitrogen atoms of proteins to form an adduct, which can be detected by changes in fluorescence or by x-ray crystallography. The structures of 2HNP and its adducts have been determined using x-ray crystal structures and high performance liquid chromatography (HPLC).

• Brand: Biosynth

Chemical properties

• Molecular weight: 109.13 g/mol
• Formula: C₅H₇N₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C5H7N3/c6-8-5-3-1-2-4-7-5/h1-4H,6H2,(H,7,8)
• InChI key: InChIKey=NWELCUKYUCBVKK-UHFFFAOYSA-N
• SMILES: NNc1ccccn1