6-Hydroxypicolinic acid

CAS: 19621-92-2

Ref. 3D-FH33042

Product Information

• Name: 6-Hydroxypicolinic acid
• Synonyms: 6-Hydroxy-2-pyridine carboxylic acid, 1,6-Dihydro-6-oxo-2-pyridinecarboxylic acid, 2-Hydroxy-6-PyridineCarboxylicAcid, 2-Hydroxypyridine-6-carboxylic acid, 2-Oxo-1,2-dihydropyridine-6-carboxylic acid, 2-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-, 6-Hydroxy-2-PyridineCarboxylicAcid, 6-Hydroxy-2-picolinic acid, 6-Hydroxypyridine-2-carboxylic acid, 6-Oxo-1,6-Dihydropyridine-2-Carboxylate, 6-Oxo-1,6-Dihydropyridine-2-Carboxylic Acid, 6-Oxo-1,6-Dihydropyridine-3-Carboxylic Acid, 6-Oxo-1H-pyridine-2-carboxylicacid, 6-Oxopyridine-2-carboxylic acid, NSC 51589, Picolinic acid, 1,6-dihydro-6-oxo-, Picolinic acid, 6-hydroxy-

Description

6-Hydroxypicolinic acid is a hydroxylated derivative of picolinic acid that has been shown to be a potent inhibitor of microbial metabolism. It is an intermediate in the catabolism of picolinic acid, which is formed by the oxidation of tryptophan. The compound can be synthesized from 6-hydroxypyridine and picolinic acid. 6-Hydroxypicolinic acid inhibits bacterial growth by binding to the enzyme nicotinamidase, which catalyzes the final step in cellular nicotinamide adenine dinucleotide (NAD) biosynthesis. This prevents NAD from being converted into nicotinamide adenine dinucleotide phosphate (NADP), thereby disrupting the redox balance within cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 139.11 g/mol
• Formula: C₆H₅NO₃
• Purity: Min. 95%