N-(Hydroxymethyl)phthalimide

CAS: 118-29-6

Ref. 3D-FH33638

Product Information

• Name: N-(Hydroxymethyl)phthalimide
• Synonyms: 1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-, 2-(Hydroxymethyl)-1H-Isoindole-1,3(2H)-Dione, 2-(Hydroxymethyl)-1H-Isoindole-3(2H)-Dione, 2-(Hydroxymethyl)-2,3-dihydro-1H-isoindole-1,3-dione, 2-(Hydroxymethyl)isoindoline-1,3-dione, 2-Hydroxymethyl-isoindole-1,3-dione, Akos Bbs-00004724, Aurora Ka-454, Hydroxymethyl Phthalimide, Iflab-Bb F0777-0575, Methanol, phthalimido-, N-(Hydroxymethyl)-Phthalimid, N-Methylolphthalimide, NSC 27350, NSC 27471, NSC 39723, Oxymethyl phthalimide, Phthalimide, N-(hydroxymethyl)-, Phthalimidomethanol, Phthalimidomethyl alcohol
• CAS: 118-29-6

Description

N-(Hydroxymethyl)phthalimide is a carbonyl-containing compound that has acidic properties. It can be used as a precursor to the synthesis of nonsteroidal anti-inflammatory drugs. N-(Hydroxymethyl)phthalimide is stable in basic solutions and hydrolyzes in acidic environments. It is also soluble in organic solvents such as chloroform, methylene chloride, and dimethyl sulfoxide. N-(Hydroxymethyl)phthalimide's antiinflammatory activity may be due to its ability to inhibit prostaglandin synthesis by inhibiting amine oxidase.

N-(Hydroxymethyl)phthalimide inhibits prostaglandin synthesis by inhibiting amine oxidase, which catalyzes the conversion of amines into acid metabolites through oxidation reactions. This process leads to an increase in the concentration of H+ ions in cells, which activates other enzymes that are involved with inflammation, such as cyclooxygenases and

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.16 g/mol
• Formula: C₉H₇NO₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C9H7NO3/c11-5-10-8(12)6-3-1-2-4-7(6)9(10)13/h1-4,11H,5H2
• InChI key: InChIKey=MNSGOOCAMMSKGI-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2C(=O)N1CO