2-(4-Hydroxybenzoyl)benzoic acid

CAS: 85-57-4

Ref. 3D-FH33825

Product Information

• Name: 2-(4-Hydroxybenzoyl)benzoic acid
• Synonyms: 2-(4-hydroxybenzoyI)benzoic acid, 201-616-4, 4′-Hydroxy-2-benzoylbenzoic acid, Benzoic acid, 2-(4-hydroxybenzoyl)-, Benzoic acid, o-(p-hydroxybenzoyl)-, Hibenzate, NSC 122980, NSC 57609, Phthalein acid, o-(p-Hydroxybenzoyl)benzoic acid

Description

2-(4-Hydroxybenzoyl)benzoic acid (HBBA) is an activated ester that can be used as a precursor for the synthesis of pharmaceuticals. It has been used in the clinical development of drugs such as anti-inflammatory agents, antibiotics, and anticancer compounds. HBBA can be synthesized by acylation of 4-hydroxybenzoic acid with an appropriate carboxylic acid via a dehydration reaction. This reaction requires high temperatures and acidic catalysts. The product is then purified to remove any residual acid catalyst and other impurities. 2-(4-Hydoxybenzoyl)benzoic acid has been shown to react with nucleophiles such as amines and alcohols, providing fluorescent compounds when reacted with diazonium salts or phthalazinone respectively.

• Brand: Biosynth

Chemical properties

• Molecular weight: 242.23 g/mol
• Formula: C₁₄H₁₀O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C14H10O4/c15-10-7-5-9(6-8-10)13(16)11-3-1-2-4-12(11)14(17)18/h1-8,15H,(H,17,18)
• InChI key: InChIKey=YGTUPRIZNBMOFV-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccccc1C(=O)c1ccc(O)cc1