Hexamethonium bromide

CAS: 55-97-0

Ref. 3D-FH34254

Product Information

• Name: Hexamethonium bromide
• Synonyms: 1,6-Bis(trimethylammonium)hexane dibromide, 1,6-Hexanebis(trimethylammonium) dibromide, 1,6-Hexanediaminium, N,N,N,N′,N′,N′-hexamethyl-, dibromide, 1,6-Hexanediaminium, N¹,N¹,N¹,N⁶,N⁶,N⁶-hexamethyl-, bromide (1:2), Ammonium, hexamethylenebis[trimethyl-, dibromide, Bistrium bromide, Esametina, Gangliostat, Hexamethone bromide, Hexamethonium bromide hydrate, Hexamethonium dibromide, Hexamethylenebis(trimethylammonium bromide) hydrate, Hexamethylenebis(trimethylammonium) dibromide, Hexamethylenebis[trimethylammonium bromide], Hexameton, Hexameton bromide, Hexane-1,6-bis(trimethylammonium bromide), Hexanium bromide, Hexonium dibromide, Methobromin, Methobromine, N,N,N,N',N',N'-Hexamethylhexane-1,6-diammonium dibromide, N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium dibromide, N,N,N,N′,N′,N′-Hexamethyl(hexamethylene)diammonium bromide, Simpatoblock, Vegolysen, Vegolysin, C 6, 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, bromide (1:2)

Description

Hexamethonium bromide is a nicotinic receptor antagonist that blocks the action of acetylcholine at the neuromuscular junction. It is used in medicine to treat respiratory failure, bowel disease and autoimmune diseases. Hexamethonium bromide has been shown to inhibit the production of inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), in vivo by blocking acetylcholine receptors. This drug also decreases the glomerular filtration rate and slows down bowel movements. Hexamethonium bromide also has a beneficial effect on symptoms associated with bladder cancer.
This drug binds to acetylcholine receptors on cells, which are found in large numbers in muscles, heart, and bladder.

• Brand: Biosynth

Chemical properties

• Molecular weight: 362.19 g/mol
• Formula: C₁₂H₃₀Br₂N₂
• Purity: Min. 95%
• Color/Form: Powder