Hexahydroisonicotinamide

CAS: 39546-32-2

Ref. 3D-FH34632

Product Information

• Name: Hexahydroisonicotinamide
• Synonyms: Isonipecotamide, 4-(Aminocarbonyl)piperidine, 4-Carbamoylpiperidine, 4-Carbamoylpiperidinium, 4-Carboxamidopiperidine, 4-Piperidinecarboxamide, 4-Piperidylcarboxamide, NSC 82318, Piperidine-4-Carboxamide, Piperidine-4-carboxylic acid amide

Description

Hexahydroisonicotinamide (HNI) is a potent amyloid protein inhibitor that is structurally related to picolinic acid. HNI has been shown to be effective in the treatment of infectious diseases caused by bacteria, such as diazonium salt-resistant strains of Pseudomonas aeruginosa and Enterobacter cloacae. Hexahydroisonicotinamide is also active against methicillin-resistant Staphylococcus aureus (MRSA), which may be due to its structural similarity to picolinic acid. The molecular weight of HNI is 587.6, with a molecular formula of C9H11N3O2. It has been shown that hexahydroisonicotinamide inhibits the transfer reaction between an amide and piperidinium, as well as the phosphorylation of proteins by enzyme kinases. This drug binds to hydrated biphenyl molecules and inhibits their

• Brand: Biosynth

Chemical properties

• Molecular weight: 128.17 g/mol
• Formula: C₆H₁₂N₂O
• Purity: Min. 95%
• Color/Form: White To Yellow Solid
• InChI: InChI=1S/C6H12N2O/c7-6(9)5-1-3-8-4-2-5/h5,8H,1-4H2,(H2,7,9)
• InChI key: InChIKey=DPBWFNDFMCCGGJ-UHFFFAOYSA-N
• SMILES: NC(=O)C1CCNCC1