5-Hydroxymethylcytosine

CAS: 1123-95-1

Ref. 3D-FH35238

Product Information

• Name: 5-Hydroxymethylcytosine
• Synonyms: 2(1H)-Pyrimidinone, 4-amino-5-(hydroxymethyl)-, 2(1H)-Pyrimidinone, 6-amino-5-(hydroxymethyl)-, 2-Hydroxy-4-Amino-5-(Hydroxymethyl)Pyrimidine, 4-Amino-2-hydroxy-5-pyrimidinemethanol, 4-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone, 4-Amino-5-(hydroxymethyl)pyrimidin-2-ol, 4-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one, 5-(Hydroxymethyl)cytosine, 5-(Oxymethyl)cytosine, 6-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone, 6-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one, Cytosine, 5-(hydroxymethyl)-, Demethylbacimethrin, NSC 27368

Description

5-Hydroxymethylcytosine is a metabolite of the nucleic acid cytosine. It is an epigenetic modification that alters gene expression without changing the DNA sequence. 5-Hydroxymethylcytosine has been shown to be a potential biomarker of cellular transformation and is involved in axonal growth, transcriptional regulation, and leukemia inhibitory factor. 5-Hydroxymethylcytosine binds to nuclear dna, which inhibits replication by binding to the duplexes of dna (the double helix) and halting transcriptional elongation. 5-Hydroxymethylcytosine also binds cell factor, which is necessary for cell proliferation and differentiation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 141.13 g/mol
• Formula: C₅H₇N₃O₂
• Purity: Min. 95 Area-%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C5H7N3O2/c6-4-3(2-9)1-7-5(10)8-4/h1,9H,2H2,(H3,6,7,8,10)
• InChI key: InChIKey=RYVNIFSIEDRLSJ-UHFFFAOYSA-N
• SMILES: Nc1[nH]c(=O)ncc1CO