Hydrocortisone sodium phosphate

CAS: 6000-74-4

Ref. 3D-FH36999

Product Information

• Name: Hydrocortisone sodium phosphate
• Synonyms: Cleiton, Cortisol 21-phosphate disodium salt, Cortisol sodium phosphate, Cortisol, 21-(dihydrogen phosphate), disodium salt, Disodium (11Beta)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Phosphate, Disodium (8Xi,9Xi,10Xi,13Xi,14Xi)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Phosphate, Disodium hydrocortisone 21-phosphate, Efcortesol, Hydrocortisone 21-disodium phosphate, Hydrocortisone 21-disodium salt, Hydrocortisone 21-phosphate disodium, Hydrocortisone 21-phosphate disodium salt, Hydrocortisone 21-sodium phosphate, Hydrocortisone Sodium Phosphate, Hydrocortisone disodium phosphate, Hydrocortone phosphate, Physiocortison, Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11β)-, Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, sodium salt (1:2), (11β)-, Sodium cortisol 21-phosphate, Sodium hydrocortisone 21-phosphate

Description

Hydrocortisone sodium phosphate is a potent anti-inflammatory agent that belongs to a class of drugs called corticosteroids. It is used to treat inflammatory bowel disease, rheumatoid arthritis, and other autoimmune diseases. Hydrocortisone sodium phosphate inhibits the production of cytokines and mediators of inflammation by inhibiting the activity of leukocytes such as human polymorphonuclear leukocytes (PMN) and lymphocytes. Hydrocortisone sodium phosphate also has antimicrobial effects against bacteria that are sensitive to this drug. This agent is metabolized in vivo to hydrocortisone by esterases, which are found in the kidney, liver, or gut wall. Hydrocortisone sodium phosphate can inhibit drug metabolism by cytochrome P450 enzymes (CYP3A4).

• Brand: Biosynth

Chemical properties

• Molecular weight: 486.4 g/mol
• Formula: C₂₁H₂₉Na₂O₈P
• Purity: Min. 95%
• Color/Form: White Powder