1-Hydroxypyridine-2-thione zinc

CAS: 13463-41-7

Ref. 3D-FH40903

Product Information

• Name: 1-Hydroxypyridine-2-thione zinc
• Synonyms: (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS²]zinc, 1-Hydroxy-2-Pyridinthion-Zn(Ii)-Salz, 1-Hydroxy-2-pyridinethione, zinc salt, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Mercaptopyridine N-oxide zinc salt, 2-Pyridinethiol 1-oxide zinc salt, 2-Pyridinethiol N-oxide zinc salt, 2-Pyridylthiol-1-oxide zinc salt, Af-Z, Bc-J, Biocut ZP, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol 1-oxide)zinc, Clean-Bio ZP, Danex, Dantrol, Denistat ANK, Desquaman, Evafine P 50, Finecide ZPT, Fsb 8332, Hokucide ZPT, Hybricide 89, Intercide ZNP, Marukacide YP-DP, Mercaptopyridinenoxidezincsalt, Microban Additive ZO 1, Microban Z 01, Niccanon SKT, Niccanon ZP, Nsc 290409, Om 1563, Omadine Zinc, Piritionato Cincico, Pyrithione Zinc, Pyrithione zincique, Pyrithionzink, Ruco-Bac Zpy, Sanaizol 200, Sanitized TH 22-27, Sanitized TH 27-24BT, Sebulon Shampoo, Slaoff 94, Slaoff 95, Sr-A 103, Th 22-27, Tomicide Z 50, Tomicide ZPT, Tomicide ZPT 100, Tomicide ZPT 50, Vancide P, Vedexil-PZ, ZNP Bar, ZPT, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-Pyridinethiol-1-Oxide, Zinc 2-mercaptopyridine N-oxide, Zinc Bis(1,2-Dihydro-2-Thioxo-1-Pyridyl) Dioxide, Zinc Bis(2-Pyridithio-1-Oxide), Zinc Bis(Pyridine-2-Thiol) Di-1-Oxide, Zinc Bis(Pyridine-2-Thiolate 1-Oxide), Zinc Omacide ZOE, Zinc Omadine, Zinc Omadine ZOE, Zinc Omadine ZOE Dispersion, Zinc Pyrithione, Zinc bis (2-pyridylthio-1-oxide), Zinc bis(2-mercaptopyridine-N-oxide), Zinc pyrethion, Zinc pyridine-2-thione-N-oxide, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-, Zinc, bis(2-pyridinethiolato)-, N,N-dioxide, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-, (T-4)-, Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS²]-, (T-4)-, Zinc-Pyrion, Zincopan, Zincpolyanemine, Zn Omadine ZOE, Zo-E, Zoe-T, zinc bis(2-thioxopyridin-1(2H)-olate)

Description

Zinc pyrithione is a chemical compound that can be used as an antifungal agent. It has been shown to have genotoxic activity in vitro and in vivo. Zinc pyrithione binds to the surface of the fungal cell wall and inhibits the synthesis of ergosterol, a component of the fungal cell membrane. This binding prevents the formation of an ergosterol-zinc complex with cytochrome P450 enzymes, which are required for sterol biosynthesis, leading to inhibition of energy metabolism. The model system for zinc pyrithione is a mixture of 1-hydroxypyridine-2-thione (1HP) and zinc ions in water. Some studies have shown that zinc pyrithione can cause long-term toxicity, including glycol ether toxicity, when applied topically on hair or skin. Acute toxicities may include skin irritation or contact dermatitis from shampoos containing this substance.

• Brand: Biosynth

Chemical properties

• Molecular weight: 317.69 g/mol
• Formula: C₁₀H₈N₂O₂S₂Zn
• Purity: Min. 95%
• Color/Form: White/Off-White Solid